GHK-cu Copper Tripeptide
GHK-Cu's effectiveness in increasing collagen and elastin production, reducing wrinkles significantly compared to other commercial products.
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Benefits of GHK-Cu:
- Skin Regeneration:
- Wound Healing: Promotes faster wound healing and repair by stimulating the production of collagen and other extracellular matrix components.
- Anti-Aging: Improves skin elasticity, reduces wrinkles, and enhances overall skin appearance by promoting collagen production.
- Anti-Inflammatory: Reduces inflammation and redness in the skin, which can help with conditions like acne and rosacea.
- Antioxidant: Protects the skin from oxidative damage caused by free radicals.
- Hair Growth: Encourages hair growth by increasing the size of hair follicles and stimulating their activity.
- Improved Skin Tone: Helps to even out skin tone and reduce hyperpigmentation.
Research on GHK-Cu (glycyl-l-histidyl-l-lysine-copper) capsules and formulations reveals significant potential in wound healing, skin regeneration, and anti-aging applications. Sharma et al. (2022) synthesized a biocompatible polymer for controlled release of GHK-Cu, showing promising results in wound healing both in vitro and in vivo, with effective encapsulation and release properties【(Sharma et al., 2022)】. Pickart et al. (2015) discussed GHK-Cu's role in preventing oxidative stress in the skin by regulating copper levels and altering gene expressions to promote antioxidant activities【(Pickart et al., 2015)】. Wang et al. (2017) demonstrated that GHK-Cu liposomes significantly accelerated wound healing in mice by enhancing cell proliferation and angiogenesis【(Wang et al., 2017)】. Another study by Sharma et al. (2017) emphasized the development of a superabsorbent polymer for the controlled release of GHK-Cu, beneficial for diabetic and chronic wound care【(Sharma et al., 2017)】. Badenhorst et al. (2016) highlighted GHK-Cu's effectiveness in increasing collagen and elastin production, reducing wrinkles significantly compared to other commercial products【(Badenhorst et al., 2016)】.Detailed Comparison of Papers
Serial Number | Paper Title | Insight | Citations |
---|---|---|---|
1 | Effects of GHK-Cu on MMP and TIMP Expression, Collagen and Elastin Production, and Facial Wrinkle Parameters (Badenhorst et al., 2016) | GHK-Cu significantly enhances collagen and elastin production, reducing facial wrinkles more effectively than other products. | 13 |
2 | GHK-Cu may Prevent Oxidative Stress in Skin by Regulating Copper and Modifying Expression of Numerous Antioxidant Genes (Pickart et al., 2015) | GHK-Cu regulates copper and gene expression to prevent oxidative stress, improve skin health, and support tissue regeneration. | 16 |
3 | GHK-Cu-liposomes accelerate scald wound healing in mice by promoting cell proliferation and angiogenesis (Wang et al., 2017) | GHK-Cu liposomes significantly accelerate wound healing by enhancing cell proliferation and angiogenesis in mice, indicating potential for skin rejuvenation. | 18 |
4 | Polyaspartic acid, 2-acrylamido-2-Methyl propane sulfonic acid and sodium alginate based biocompatible stimuli responsive polymer gel for controlled release of GHK-Cu peptide for wound healing (Shilpa Sharma, 2022) | Developed a biocompatible polymer gel for effective encapsulation and controlled release of GHK-Cu, enhancing wound healing, which can be applied in anti-aging skincare. | - |
5 | Biocompatible stimuli responsive superabsorbent polymer for controlled release of GHK-Cu peptide for wound dressing application (Sharma et al., 2017) | Developed a superabsorbent polymer for controlled release of GHK-Cu, suitable for diabetic and chronic wound care, with implications for anti-aging treatments. | 21 |
- Amino SequenceGly-His-Lys
- CAS49557-75-7
- Molecular FormulaC14H22CuN6O4 (Cu complex)
- Molecular Weight340.38 g/mol
- PubChem CID378611
- SynonmsGlycyl-L-Histidyl-L-Lysine; Growth-modulating peptide; Kollaren; Liver cell growth factor; Liver growth factor Cu-GHK; Glycyl-histidyl-lysine, monocopper salt
- ManufacturerAminoBox
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