GHK-cu
GHK-Cu copper peptide is a potent bioactive molecule with significant benefits for skin and hair health.
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GHK-Cu, also known as Copper Peptide, is a small, naturally occurring protein fragment composed of three amino acids (glycine-histidine-lysine) that binds to copper ions. It has gained popularity in the cosmetic and skincare industry due to its numerous beneficial properties. Here’s a detailed overview:
Benefits of GHK-Cu Copper Peptide:
Wound Healing:
- Promotes faster healing of wounds by enhancing the body's natural repair processes.
- Stimulates the production of collagen and glycosaminoglycans, which are essential for skin repair and regeneration.
Anti-Aging:
- Reduces the appearance of fine lines and wrinkles by boosting collagen and elastin production.
- Improves skin elasticity and firmness, resulting in a more youthful appearance.
Antioxidant Properties:
- Protects skin cells from oxidative damage caused by free radicals.
- Helps in reducing inflammation and redness, making it beneficial for sensitive or irritated skin.
Skin Tightening and Firming:
- Enhances skin density and thickness, leading to a more toned and firm appearance.
- Reduces sagging by improving the skin’s structural integrity.
Hair Growth:
- Stimulates hair follicles, promoting hair growth and reducing hair loss.
- Improves the health and strength of the hair.
Skin Repair and Regeneration:
- Encourages the production of healthy skin cells, aiding in the repair of damaged skin.
- Reduces the appearance of scars and stretch marks by promoting even skin tone and texture.
Mechanisms of GHK-cu Peptide Action:
Gene Expression:
- GHK-Cu influences the expression of multiple genes involved in healing, antioxidant defense, and anti-inflammatory processes.
- It upregulates genes associated with tissue remodeling, including those coding for collagen, elastin, and proteoglycans.
- Downregulates genes linked to oxidative stress and inflammation.
Collagen Synthesis:
- Enhances the production of type I and type III collagen in fibroblasts.
- Stimulates the proliferation and migration of fibroblasts, which are essential for wound healing and skin regeneration.
Anti-Inflammatory Effects:
- Reduces the production of pro-inflammatory cytokines such as IL-1, IL-6, and TNF-α.
- Modulates the activity of inflammatory pathways, leading to reduced inflammation and accelerated healing.
Antioxidant Defense:
- Increases the expression of antioxidant enzymes like superoxide dismutase (SOD) and catalase.
- Neutralizes reactive oxygen species (ROS), protecting cells from oxidative damage.
Angiogenesis:
- Promotes the formation of new blood vessels (angiogenesis) by upregulating vascular endothelial growth factor (VEGF).
- Enhances the supply of oxygen and nutrients to damaged tissues, facilitating repair and regeneration.
Scientific Studies of GHK-cu Peptide:
>Wound Healing:
- A study published in the
Journal of Investigative Dermatology (2001) showed that GHK-Cu accelerates wound healing in rat models by increasing collagen synthesis and cell proliferation. - Another study in
Plastic and Reconstructive Surgery (1988) demonstrated improved wound healing and reduced scar formation in humans treated with GHK-Cu.
- A study published in the
Anti-Aging:
- A study in the
International Journal of Cosmetic Science (2003) reported that topical application of GHK-Cu reduced wrinkles, increased skin density, and improved overall skin appearance in volunteers. - Research published in
Mechanisms of Ageing and Development (2009) highlighted GHK-Cu’s ability to restore gene expression profiles in aged human skin to a more youthful state.
- A study in the
Hair Growth:
- An investigation in the
Journal of Dermatological Science (1993) found that GHK-Cu stimulates hair growth by prolonging the anagen (growth) phase of hair follicles in mice. - Clinical trials have shown promising results in using GHK-Cu for treating androgenetic alopecia (pattern hair loss).
- An investigation in the
GHK-cu Peptide for sale
GHK-Cu copper peptide is a potent bioactive molecule with significant benefits for skin and hair health. Its ability to modulate gene expression, stimulate collagen production, reduce inflammation, and promote healing makes it a valuable ingredient in both cosmetic and medical applications. The extensive body of scientific research supports its efficacy and safety, making it a promising component in the development of advanced skincare and therapeutic products.
- CAS49557-75-7
- SequenceGlycyl-L-Histidyl-L-Lysine
- Molecular FormulaC14H24N6O4
C14H22CuN6O4 (Cu complex) - Molecular Weight340.38 g/mol
- PubChem SID378611 (Cu complex)
- SynonymsGrowth-modulating peptide; Kollaren; Liver cell growth factor; Liver growth factor Cu-GHK; Glycyl-histidyl-lysine, monocopper salt
- ManufacturerAMINOBOX
- Mel StarJul 2, 2024, 03:26My hair is out of this world. Regrowth is looking amazing.
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USA Time Frames
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DHL | 1-2 Business Days | 10:00 AM PST |
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