Melanostatine-5 | Nonapeptide-1
Melanostatine-5 is a synthetic peptide that mimics a part of the α-MSH sequence. By occupying the MC1-R receptor, it effectively blocks the action of α-MSH, reducing melanin production by up to 33%.
Directions:
Pour contents (100mg) into 2 oz serum for 5% active peptide.
Pour contents (200mg) into 2 oz serum for strong 10% active peptide.
Add as many peptides as desired.
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Buy Melanostatine-5
Overview: Melanostatine-5, also known as Nonapeptide-1, is a biomimetic peptide that serves as an antagonist to α-MSH (alpha-Melanocyte-Stimulating Hormone). It is specifically designed to inhibit melanin synthesis and prevent hyperpigmentation, making it an effective skin-lightening agent without cytotoxic effects on melanocytes.
Mechanism of Action: Melanostatine-5 works by blocking the activation of the MC1-R receptor on melanocytes, which prevents the activation of tyrosinase, a crucial enzyme in the melanin production pathway. This inhibition leads to a reduction in melanin synthesis, thereby decreasing pigmentation and promoting an even skin tone.
Benefits of Nonapeptide-1:
- Skin Lightening: Reduces sun spots, freckles, and other forms of hyperpigmentation, leading to a lighter and more uniform complexion.
- Safe and Effective: Does not interfere with the normal function of melanocytes, ensuring it is safe for regular use.
- Proven Results: Studies have shown significant improvement in skin lightening within 28 days of regular use
(www.personalcaremagazine.com). - Versatility: Suitable for various cosmetic formulations targeting skin brightening and evening skin tone
(Amvigor Organics -).
Usage:
- Concentration: Typically used in concentrations ranging from 4.0% to 8.0% in cosmetic formulations.
- Applications: Ideal for serums, creams, and other topical products aimed at reducing hyperpigmentation and promoting skin radiance.
Certifications:
- Preservative-free
- Vegan compatible
Scientific Background:
Melanostatine-5 is a synthetic peptide that mimics a part of the α-MSH sequence. By occupying the MC1-R receptor, it effectively blocks the action of α-MSH, reducing melanin production by up to 33% (INCI Guide).
Key Points of Melanostatine-5:
- Reduce hyperpigmentation and even out skin tone.
- Safe and lack of cytotoxic effects on melanocytes.
- Proven results and scientific backing.
- Compatible with various formulations and its preservative-free with vegan status.
- CAS158563-45-2
- SequenceMet-Pro-Phe-Arg-Trp-Phe-Lys-Pro-Val-NH2
- Molecular FormulaC61H87N15O9S
- Molecular Weight1206.50 g/mol
- PubChem CID4475164
- SynonymsNonapeptide-1
- Net Weight100mg, 200mg
- ManufacturerAminoBox
- Janet FerrisJul 15, 2024, 23:29Love this. really makes my skin so white n clear. the potency to this product compared to expensive 'sephora' brands is ridiculous. Makes me feel stupid for going there before when now i can quadruple doople the active peptide product and for a way more cost effective way.
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